Human Islet 1 (ISL1) activation kit by CRISPRa

SKU
GA102461
ISL1 CRISPRa kit - CRISPR gene activation of human ISL LIM homeobox 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ISL1
Locus ID 3670
Components

GA102461G1, Islet 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102461G2, Islet 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102461G3, Islet 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002202
UniProt ID P61371
Synonyms Isl-1; ISLET1
Summary This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN406893 ISL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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