Human 5HT3A receptor (HTR3A) activation kit by CRISPRa

SKU
GA102287
HTR3A CRISPRa kit - CRISPR gene activation of human 5-hydroxytryptamine receptor 3A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HTR3A
Locus ID 3359
Components

GA102287G1, 5HT3A receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102287G2, 5HT3A receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102287G3, 5HT3A receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000869, NM_001161772, NM_213621, NR_046363
UniProt ID P46098
Synonyms 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3
Summary The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN401342 HTR3A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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