Human 5 HT 2A (HTR2A) activation kit by CRISPRa

SKU
GA102284
HTR2A CRISPRa kit - CRISPR gene activation of human 5-hydroxytryptamine receptor 2A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HTR2A
Locus ID 3356
Components

GA102284G1, 5 HT 2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102284G2, 5 HT 2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102284G3, 5 HT 2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000621, NM_001165947
UniProt ID P28223
Synonyms 5-HT2A; HTR2
Summary This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN410182 HTR2A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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