Human HMGA1 activation kit by CRISPRa

SKU GA102154

HMGA1 CRISPRa kit - CRISPR gene activation of human high mobility group AT-hook 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: HMGA1
• Locus ID: 3159
• Components:

  GA102154G1, HMGA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102154G2, HMGA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102154G3, HMGA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001319077, NM_001319078, NM_001319079, NM_001319080, NM_001319081, NM_001319082, NM_002131, NM_145899, NM_145900, NM_145901, NM_145902, NM_145903, NM_145904, NM_145905
• UniProt ID: P17096
• Synonyms: HMG-R; HMGA1A; HMGIY
• Summary: This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]