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Human HEXA activation kit by CRISPRa

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SKU
GA102095
HEXA CRISPRa kit - CRISPR gene activation of human hexosaminidase subunit alpha
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA366560 HEXA rabbit polyclonal antibody
100 ul
$310.00
RC203185 HEXA (Myc-DDK-tagged)-Human hexosaminidase A (alpha polypeptide) (HEXA)
10 ug
$492.00

Other products for "HEXA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HEXA
Locus ID 3073
Components

GA102095G1, HEXA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102095G2, HEXA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102095G3, HEXA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000520, NM_001318825, NR_134869
UniProt ID P06865
Synonyms TSD
Summary This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN403185 HEXA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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