OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human Metabotropic Glutamate Receptor 2 (GRM2) activation kit by CRISPRa

Be the first to review this product
SKU
GA101967
GRM2 CRISPRa kit - CRISPR gene activation of human glutamate metabotropic receptor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA326000 Rabbit Polyclonal GluR2 Antibody
100 ul
$335.00
RC218103 GRM2 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1
10 ug
$589.00 $798.00

Other products for "GRM2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GRM2
Locus ID 2912
Components

GA101967G1, Metabotropic Glutamate Receptor 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101967G2, Metabotropic Glutamate Receptor 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101967G3, Metabotropic Glutamate Receptor 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000839, NM_001130063, NM_001349116, NM_001349117, NR_146059
UniProt ID Q14416
Synonyms GLUR2; GPRC1B; mGlu2; MGLUR2
Summary L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2017
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN418103 GRM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products