Human GLUR3 (GRIA3) activation kit by CRISPRa

SKU
GA101948
GRIA3 CRISPRa kit - CRISPR gene activation of human glutamate ionotropic receptor AMPA type subunit 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GRIA3
Locus ID 2892
Components

GA101948G1, GLUR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101948G2, GLUR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101948G3, GLUR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000828, NM_001256743, NM_007325, NM_181894
UniProt ID P42263
Synonyms GluA3; GLUR-C; GLUR-K3; GLUR3; GLURC; MRX94
Summary Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN419063 GRIA3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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