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Human GCSH activation kit by CRISPRa

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SKU
GA101772
GCSH CRISPRa kit - CRISPR gene activation of human glycine cleavage system protein H
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA376526 GCSH Rabbit polyclonal Antibody
100 ul
$410.00
RC217886 GCSH (Myc-DDK-tagged)-Human glycine cleavage system protein H (aminomethyl carrier) (GCSH), nuclear gene encoding mitochondrial protein, transcript variant 1
10 ug
$300.00

Other products for "GCSH"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GCSH
Locus ID 2653
Components

GA101772G1, GCSH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101772G2, GCSH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101772G3, GCSH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004483, NR_033249
UniProt ID P23434
Synonyms GCE; NKH
Summary Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.provided by RefSeq, Jan 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN417886 GCSH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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