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Human Factor VII (F7) activation kit by CRISPRa

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SKU
GA101501
F7 CRISPRa kit - CRISPR gene activation of human coagulation factor VII
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC213143 F7 (Myc-DDK-tagged)-Human coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant 2
10 ug
$457.00

Other products for "F7"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol F7
Locus ID 2155
Components

GA101501G1, Factor VII gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101501G2, Factor VII gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101501G3, Factor VII gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000131, NM_001267554, NM_019616, NR_051961
UniProt ID P08709
Synonyms SPCA
Summary This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. provided by RefSeq, Aug 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN213143 F7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213143BN F7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213143LP F7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213143RB F7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413143 F7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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