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Human EPO activation kit by CRISPRa

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SKU
GA101435
EPO CRISPRa kit - CRISPR gene activation of human erythropoietin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA812059 EPO mouse monoclonal antibody,clone OTI5D8 100 ul
$447.00
RC210775 EPO (Myc-DDK-tagged)-Human erythropoietin (EPO)
10 ug
$450.00

Other products for "EPO"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol EPO
Locus ID 2056
Components

GA101435G1, EPO gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101435G2, EPO gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101435G3, EPO gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000799
UniProt ID P01588
Synonyms EP; MVCD2
Summary This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN410775 EPO - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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