Human EDG1 (S1PR1) activation kit by CRISPRa

SKU
GA101324
S1PR1 CRISPRa kit - CRISPR gene activation of human sphingosine-1-phosphate receptor 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol S1PR1
Locus ID 1901
Components

GA101324G1, EDG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101324G2, EDG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101324G3, EDG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001400, NM_001320730
UniProt ID P21453
Synonyms CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1
Summary The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN404608 S1PR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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