Human Dystrobrevin beta (DTNB) activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | DTNB |
| Locus ID | 1838 |
| Components |
GA101288G1, Dystrobrevin beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101288G2, Dystrobrevin beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101288G3, Dystrobrevin beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001256303, NM_001256304, NM_001256308, NM_021907, NM_033147, NM_033148, NM_183360, NM_183361, NM_001320932, NM_001320933, NM_001320934, NM_001320935, NM_001320936, NM_001320937, NM_001351381, NM_001351382, NM_001351383, NM_001351384, NM_001351385, NM_001351386, NM_001351387, NM_001351388, NM_001351389, NM_001351390, NM_001351391, NM_001351392, NM_001351393, NM_001351394, NM_001351395, NR_147180 |
| UniProt ID | O60941 |
| Summary | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. provided by RefSeq, Mar 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN403798 | DTNB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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