Human DOPA Decarboxylase (DDC) activation kit by CRISPRa

SKU
GA101159
DDC CRISPRa kit - CRISPR gene activation of human dopa decarboxylase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DDC
Locus ID 1644
Components

GA101159G1, DOPA Decarboxylase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101159G2, DOPA Decarboxylase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101159G3, DOPA Decarboxylase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000790, NM_001082971, NM_001242886, NM_001242887, NM_001242888, NM_001242889, NM_001242890
UniProt ID P20711
Synonyms AADC
Summary The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. provided by RefSeq, Jun 2011
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Documents
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Other Versions
SKU Description Size Price
KN401345 DDC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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