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Human CYP7A1 activation kit by CRISPRa

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SKU
GA101111
CYP7A1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 7 subfamily A member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC211019 CYP7A1 (Myc-DDK-tagged)-Human cytochrome P450, family 7, subfamily A, polypeptide 1 (CYP7A1)
10 ug
$469.00

Other products for "CYP7A1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CYP7A1
Locus ID 1581
Components

GA101111G1, CYP7A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101111G2, CYP7A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101111G3, CYP7A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000780
UniProt ID P22680
Synonyms CP7A; CYP7; CYPVII
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. provided by RefSeq, Feb 2010
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Documents
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Other Versions
SKU Description Size Price
KN411019 CYP7A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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