Human CYP2D7 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CYP2D7 |
| Locus ID | 1564 |
| Components |
GA101102G1, CYP2D7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101102G2, CYP2D7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101102G3, CYP2D7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NG_002362, NM_001002910, NR_002570, NM_001348386, NR_145674 |
| Synonyms | CYP2D; CYP2D@; P450C2D; P450DB1 |
| Summary | This gene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is a segregating pseudogene, where some individuals may have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. In this case, the functional allele is thought to be rare. This locus is part of a cluster of cytochrome P450 genes on chromosome 22. provided by RefSeq, Jan 2017 |
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