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Human Cortistatin (CORT) activation kit by CRISPRa

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SKU
GA100930
CORT CRISPRa kit - CRISPR gene activation of human cortistatin
  $1,657.00
4 Weeks*

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Other products for "CORT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CORT
Locus ID 1325
Components

GA100930G1, Cortistatin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100930G2, Cortistatin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100930G3, Cortistatin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001302
UniProt ID O00230
Synonyms CST-14; CST-17; CST-29
Summary This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. provided by RefSeq, Nov 2010
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Documents
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Other Versions
SKU Description Size Price
KN422197 CORT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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