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Human CMKLR1 activation kit by CRISPRa

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SKU
GA100875
CMKLR1 CRISPRa kit - CRISPR gene activation of human chemerin chemokine-like receptor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA352007 Rabbit Polyclonal Anti-CMKLR1 Antibody
100 ul
$205.00
RC217247 CMKLR1 (Myc-DDK-tagged)-Human chemokine-like receptor 1 (CMKLR1), transcript variant 2
10 ug
$457.00

Other products for "CMKLR1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CMKLR1
Locus ID 1240
Components

GA100875G1, CMKLR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100875G2, CMKLR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100875G3, CMKLR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001142343, NM_001142344, NM_001142345, NM_004072
UniProt ID Q99788
Synonyms CHEMERINR; ChemR23; DEZ; RVER1
Summary Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN417247 CMKLR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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