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Human Choline Acetyltransferase (CHAT) activation kit by CRISPRa

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SKU
GA100785
CHAT CRISPRa kit - CRISPR gene activation of human choline O-acetyltransferase
  $1,657.00
4 Weeks*

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Other products for "CHAT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CHAT
Locus ID 1103
Components

GA100785G1, Choline Acetyltransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100785G2, Choline Acetyltransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100785G3, Choline Acetyltransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001142929, NM_001142933, NM_001142934, NM_020549, NM_020984, NM_020985, NM_020986
UniProt ID P28329
Synonyms CHOACTASE; CMS1A; CMS1A2
Summary This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. provided by RefSeq, May 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN416924 CHAT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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