Human Cofilin 1 (CFL1) activation kit by CRISPRa

SKU
GA100773
CFL1 CRISPRa kit - CRISPR gene activation of human cofilin 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CFL1
Locus ID 1072
Components

GA100773G1, Cofilin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100773G2, Cofilin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100773G3, Cofilin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005507
UniProt ID P23528
Synonyms CFL; HEL-S-15
Summary The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.supplied by OMIM, Apr 2004
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Documents
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Other Versions
SKU Description Size Price
KN403585 CFL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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