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Human LIMPII (SCARB2) activation kit by CRISPRa

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SKU
GA100672
SCARB2 CRISPRa kit - CRISPR gene activation of human scavenger receptor class B member 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA336643 Rabbit Polyclonal LIMPII/lpg85 Antibody
100 ul
$620.00
RC202162 SCARB2 (Myc-DDK-tagged)-Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1
10 ug
$457.00

Other products for "SCARB2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SCARB2
Locus ID 950
Components

GA100672G1, LIMPII gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100672G2, LIMPII gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100672G3, LIMPII gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001204255, NM_005506
UniProt ID Q14108
Synonyms AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII
Summary The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Feb 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN402162 SCARB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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