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Human Cyclin D3 (CCND3) activation kit by CRISPRa

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SKU
GA100628
CCND3 CRISPRa kit - CRISPR gene activation of human cyclin D3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350646 Rabbit Polyclonal Anti-CCND3 Antibody
100 ul
$205.00
RC202437 CCND3 (Myc-DDK-tagged)-Human cyclin D3 (CCND3), transcript variant 2
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Other products for "CCND3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCND3
Locus ID 896
Components

GA100628G1, Cyclin D3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100628G2, Cyclin D3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100628G3, Cyclin D3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001136017, NM_001136125, NM_001136126, NM_001287427, NM_001287434, NM_001760
UniProt ID P30281
Synonyms cyclin D3; D3-type cyclin; G1/S-specific cyclin D3; OTTHUMP00000016390
Summary The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402437 CCND3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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