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Human Caspase 5 (CASP5) activation kit by CRISPRa

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SKU
GA100591
CASP5 CRISPRa kit - CRISPR gene activation of human caspase 5
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210421 CASP5 (Myc-DDK-tagged)-Human caspase 5, apoptosis-related cysteine peptidase (CASP5), transcript variant a
10 ug
$457.00

Other products for "CASP5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CASP5
Locus ID 838
Components

GA100591G1, Caspase 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100591G2, Caspase 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100591G3, Caspase 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001136109, NM_001136110, NM_001136111, NM_001136112, NM_004347, NR_024239, NR_036562
UniProt ID P51878
Synonyms ICE(rel)III; ICEREL-III; ICH-3
Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. provided by RefSeq, Aug 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN410421 CASP5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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