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Human Complement C3 (C3) activation kit by CRISPRa

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SKU
GA100498
C3 CRISPRa kit - CRISPR gene activation of human complement C3
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215069 C3 (Myc-DDK-tagged)-Human complement component 3 (C3)
10 ug
$589.00 $1,422.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol C3
Locus ID 718
Components

GA100498G1, Complement C3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100498G2, Complement C3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100498G3, Complement C3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000064
UniProt ID P01024
Synonyms AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p
Summary Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. provided by RefSeq, Nov 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN415069 C3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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