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Human ATR activation kit by CRISPRa

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SKU
GA100376
ATR CRISPRa kit - CRISPR gene activation of human ATR serine/threonine kinase
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATR
Locus ID 545
Components

GA100376G1, ATR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100376G2, ATR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100376G3, ATR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001184, NM_001354579
UniProt ID Q13535
Synonyms FCTCS; FRP1; MEC1; SCKL; SCKL1
Summary The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN424837 ATR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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