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Human AARE (APEH) activation kit by CRISPRa

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SKU
GA100228
APEH CRISPRa kit - CRISPR gene activation of human acylaminoacyl-peptide hydrolase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350787 Rabbit Polyclonal Anti-APEH Antibody
100 ul
$205.00
RC200666 APEH (Myc-DDK-tagged)-Human N-acylaminoacyl-peptide hydrolase (APEH)
10 ug
$1,005.00

Other products for "APEH"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol APEH
Locus ID 327
Components

GA100228G1, AARE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100228G2, AARE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100228G3, AARE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001640
UniProt ID P13798
Synonyms AARE; ACPH; APH; D3F15S2; D3S48E; DNF15S2; OPH
Summary This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN400666 APEH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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