Human ALOX15 activation kit by CRISPRa

SKU GA100170

ALOX15 CRISPRa kit - CRISPR gene activation of human arachidonate 15-lipoxygenase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ALOX15
• Locus ID: 246
• Components:

  GA100170G1, ALOX15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100170G2, ALOX15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100170G3, ALOX15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001140
• UniProt ID: P16050
• Synonyms: 12-LOX; 15-LOX-1; 15LOX-1
• Summary: This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]