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Human ALAS1 activation kit by CRISPRa

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SKU
GA100146
ALAS1 CRISPRa kit - CRISPR gene activation of human 5'-aminolevulinate synthase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA808177 ALAS1 mouse monoclonal antibody, clone OTI1C5 (formerly 1C5) 100 ul
$447.00
RC219938 ALAS1 (Myc-DDK-tagged)-Human aminolevulinate, delta-, synthase 1 (ALAS1), transcript variant 1
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Other products for "ALAS1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ALAS1
Locus ID 211
Components

GA100146G1, ALAS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100146G2, ALAS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100146G3, ALAS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000688, NM_001304443, NM_001304444, NM_199166
UniProt ID P13196
Synonyms ALAS; ALAS-H; ALAS3; ALASH; MIG4
Summary This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jan 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN403996 ALAS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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