Human APJ Receptor (APLNR) activation kit by CRISPRa

SKU
GA100132
APLNR CRISPRa kit - CRISPR gene activation of human apelin receptor
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol APLNR
Locus ID 187
Components

GA100132G1, APJ Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100132G2, APJ Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100132G3, APJ Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005161, NR_027991
UniProt ID P35414
Synonyms AGTRL1; APJ; APJR; HG11
Summary This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. provided by RefSeq, Jul 2009
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Other Versions
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KN207576 APLNR - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN207576BN APLNR - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN207576LP APLNR - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN207576RB APLNR - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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