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Human Angiotensinogen (AGT) activation kit by CRISPRa

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SKU
GA100129
AGT CRISPRa kit - CRISPR gene activation of human angiotensinogen
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC203768 AGT (Myc-DDK-tagged)-Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
10 ug
$457.00

Other products for "AGT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol AGT
Locus ID 183
Components

GA100129G1, Angiotensinogen gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100129G2, Angiotensinogen gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100129G3, Angiotensinogen gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000029
UniProt ID P01019
Synonyms ANHU; SERPINA8
Summary The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. provided by RefSeq, Nov 2019
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Documents
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Other Versions
SKU Description Size Price
KN403768 AGT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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