Human alpha Adaptin (AP2A2) activation kit by CRISPRa

SKU GA100114

AP2A2 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 2 subunit alpha 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: AP2A2
• Locus ID: 161
• Components:

  GA100114G1, alpha Adaptin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100114G2, alpha Adaptin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100114G3, alpha Adaptin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001242837, NM_012305, NR_144509, NR_144510
• UniProt ID: O94973
• Synonyms: ADTAB; CLAPA2; HIP-9; HIP9; HYPJ
• Summary: The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016]