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IGF1 Receptor (IGF1R) (NM_000875) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC214928L4V
Lenti ORF particles, IGF1R (mGFP-tagged) - Human insulin-like growth factor 1 receptor (IGF1R), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
mGFP w/ Puro DDK mGFP DDK w/ Puro
  $2,304.00
2 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol IGF1 Receptor
Synonyms CD221; IGFIR; IGFR; JTK13
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC214928).
ACCN NM_000875
ORF Size 4101 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_000875.2
RefSeq Size 4989 bp
RefSeq ORF 4104 bp
Locus ID 3480
UniProt ID P08069
Cytogenetics 15q26.3
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Adherens junction, Colorectal cancer, Endocytosis, Focal adhesion, Glioma, Long-term depression, Melanoma, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer
MW 154.79 kDa
Summary This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, May 2014
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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