DUSP1 (NM_004417) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC205220L1V
Lenti ORF particles, DUSP1 (Myc-DDK tagged) - Human dual specificity phosphatase 1 (DUSP1), 200ul, >10^7 TU/mL
  $1,007.00
3 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol DUSP1
Synonyms CL100; HVH1; MKP-1; MKP1; PTPN10
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC205220).
ACCN NM_004417
ORF Size 1101 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_004417.2
RefSeq Size 2015 bp
RefSeq ORF 1104 bp
Locus ID 1843
UniProt ID P28562, B4DU40
Cytogenetics 5q35.1
Domains DSPc, PTPc_motif, RHOD
Protein Families Druggable Genome, Phosphatase
Protein Pathways MAPK signaling pathway
MW 39.1 kDa
Summary The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. provided by RefSeq, Aug 2017
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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