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DUSP1 Mouse Monoclonal Antibody [Clone ID: OTI4F10]

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SKU
TA812680
DUSP1 mouse monoclonal antibody,clone OTI4F10
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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Specifications
Specifications
Product Data
Clone Name OTI4F10
Application WB
Recommended Dilution WB 1:500
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human DUSP1 (NP_004408) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 39.1 kDa
Gene Name dual specificity phosphatase 1
Database Link
Background The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. provided by RefSeq, Jul 2008
Synonyms CL100; HVH1; MKP-1; MKP1; PTPN10
Reference Data
Protein Categories Chemokines, Intracellular Proteins
Protein Families Druggable Genome, Phosphatase
Protein Pathways MAPK signaling pathway
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Other "OTI4F10" antibodies (4)
SKU Description Size Price
CF812680 Carrier-free (BSA/glycerol-free) DUSP1 mouse monoclonal antibody,clone OTI4F10 100 ug
$620.00
TA812680AM DUSP1 mouse monoclonal antibody,clone OTI4F10, Biotinylated 100 ul
$509.00
TA812680BM DUSP1 mouse monoclonal antibody,clone OTI4F10, HRP conjugated 100 ul
$509.00
TA812680S DUSP1 mouse monoclonal antibody,clone OTI4F10 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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