RASD2 (NM_014310) Human Untagged Clone
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | RASD2 |
| Synonyms | Rhes; TEM2 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_014310 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_014310.3, NP_055125.2 |
| RefSeq Size | 3047 bp |
| RefSeq ORF | 801 bp |
| Locus ID | 23551 |
| UniProt ID | Q96D21 |
| Cytogenetics | 22q12.3 |
| Domains | RAB, RAN, ras, RAS, RHO |
| Protein Families | Druggable Genome |
| Summary | This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. provided by RefSeq, Jan 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_014310" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC201454 | RASD2 (Myc-DDK-tagged)-Human RASD family, member 2 (RASD2) | 10 ug |
$300.00
|
|
| RC201454L1 | Lenti ORF clone of Human RASD family, member 2 (RASD2), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC201454L2 | Lenti ORF clone of Human RASD family, member 2 (RASD2), mGFP tagged | 10 ug |
$600.00
|
|
| RC201454L3 | Lenti ORF clone of Human RASD family, member 2 (RASD2), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC201454L4 | Lenti ORF clone of Human RASD family, member 2 (RASD2), mGFP tagged | 10 ug |
$600.00
|
|
| RG201454 | RASD2 (tGFP-tagged) - Human RASD family, member 2 (RASD2) | 10 ug |
$489.00
$500.00
|
|
| SC115073 | RASD2 (untagged)-Human RASD family, member 2 (RASD2) | 10 ug |
$300.00
|
|
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