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SLC19A3 (NM_025243) Human Untagged Clone

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SKU
SC324186
SLC19A3 (untagged)-Human solute carrier family 19, member 3 (SLC19A3)
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SLC19A3
Synonyms BBGD; THMD2; thTr-2; THTR2
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_025243.3 CGGCAAGTGAGCGATTTGGTGAACAGACACTCCCTTCTGTAGCCATGGATTGTTACAGAA
CTTCACTAAGCAGTTCCTGGATTTACCCCACTGTGATCCTCTGCTTATTTGGTTTTTTCT
CCATGATGAGACCCTCAGAACCGTTCCTTATCCCATATTTATCTGGACCAGATAAAAACC
TGACCAGTGCAGAGATAACAAATGAGATCTTCCCCGTTTGGACATACTCCTACCTGGTGC
TGCTGCTGCCTGTGTTTGTCCTCACCGATTATGTCCGCTACAAGCCAGTCATCATCTTGC
AAGGTATCAGTTTCATCATTACCTGGCTGCTGCTGTTGTTTGGCCAAGGAGTGAAGACCA
TGCAGGTTGTAGAGTTCTTCTATGGGATGGTCACCGCCGCCGAGGTGGCCTACTACGCCT
ACATATACAGCGTGGTCAGCCCCGAGCACTACCAGAGAGTGAGCGGCTACTGCAGGAGCG
TCACGCTGGCCGCCTACACAGCAGGGTCGGTGCTGGCTCAACTCTTGGTATCCCTGGCGA
ACATGTCGTACTTTTACCTCAACGTCATATCCTTGGCCTCTGTCTCCGTGGCTTTCCTTT
TCTCACTTTTCCTACCAATGCCCAAGAAAAGCATGTTTTTTCATGCAAAACCCAGCAGAG
AAATAAAGAAGTCATCAAGCGTGAATCCAGTATTAGAGGAAACTCACGAAGGTGAAGCAC
CAGGCTGTGAAGAGCAGAAACCCACATCAGAAATACTCAGCACTTCAGGGAAGCTGAATA
AGGGCCAGCTGAACAGCCTGAAACCAAGCAATGTGACTGTGGACGTTTTTGTGCAGTGGT
TCCAAGATTTGAAGGAGTGCTACTCCTCAAAACGTCTTTTCTACTGGTCTCTATGGTGGG
CTTTCGCCACAGCAGGTTTTAACCAGGTTTTGAACTATGTTCAAATCCTGTGGGATTACA
AGGCGCCATCCCAAGATTCTTCCATCTATAATGGGGCCGTAGAAGCTATTGCAACCTTTG
GAGGGGCTGTGGCTGCCTTTGCAGTGGGTTATGTGAAAGTCAACTGGGACCTTCTGGGAG
AGCTGGCTCTGGTGGTCTTCTCAGTTGTCAATGCCGGTTCTTTATTTCTCATGCATTACA
CAGCCAATATCTGGGCGTGCTATGCTGGCTATTTGATATTCAAGTCCAGCTATATGCTTC
TTATAACCATAGCAGTATTTCAGATTGCAGTTAATCTGAATGTGGAACGCTATGCCTTGG
TATTTGGAATCAACACCTTTATTGCCTTGGTGATTCAGACCATCATGACTGTGATTGTAG
TAGATCAGAGAGGGCTCAACTTGCCAGTCAGCATTCAGTTTTTAGTTTATGGGAGCTATT
TTGCAGTAATTGCTGGAATTTTCCTAATGAGAAGCATGTATATTACCTACTCAACCAAAT
CCCAGAAGGATGTACAGAGCCCTGCTCCAAGTGAGAATCCAGATGTGTCTCACCCAGAGG
AAGAGAGTAATATCATCATGTCAACAAAACTCTAACCTCATCGCAACAAACGCAACAGTG
GCTTTCAAAGTTATGCAATAATAAGGAAAGATTTTGAGATGGGTGGCATATGTTTTGCCA
TAACTTGACATGCTTTGCAAATCTGGATTCCAATGGACCTTTCAAAACCACAACAAAACC
TCAGTTTTAGATGAGTTCTCTATGTGACCAATTTTACTGGATGCAATTGACAGGACCCGT
CATCATAATTAAACAACCCATATTGGGGACCCCCTGTGACTAGTAGCAGCTGGAAAATTC
TGGTTTTTATCACTTGTAAAGACATGCAGATGGCGTGGAACCAAACCATGAGAAAACTCC
AGCCATCCTGGAGTTGATATTCACCATTTGTGAGGAGAAATACTAACTGGACTGACCCTA
TTGCTAGGCTTAAATACTTATTTGATCTTACCAAAGAAGTCAACACATGGGACCTTTGTG
TCACATGAACCATTTTCTTTCCTCTTCTATTAAGTGTATTTCTGTTTAAGTTACAGTTCT
CTAAGAGAATTACAATGTTTGTCCCATTTCTAAGGGCTTCTCTTCAACTCTAATAACAGC
ATTATTCACGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites ECoRI-NOT |
ACCN NM_025243
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_025243.3, NP_079519.1
RefSeq Size 3775 bp
RefSeq ORF 1491 bp
Locus ID 80704
UniProt ID Q9BZV2
Cytogenetics 2q36.3
Domains Folate_carrier
Protein Families Transmembrane
Summary This gene encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD); a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild cognitive disability, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.provided by RefSeq, Jan 2010
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"NM_025243" in other vectors (5)
SKU Description Size Price
RC206409 SLC19A3 (Myc-DDK-tagged)-Human solute carrier family 19, member 3 (SLC19A3) 10 ug
$457.00
RC206409L3 Lenti ORF clone of Human solute carrier family 19, member 3 (SLC19A3), Myc-DDK-tagged 10 ug
$757.00
RC206409L4 Lenti ORF clone of Human solute carrier family 19, member 3 (SLC19A3), mGFP tagged 10 ug
$757.00
RG206409 SLC19A3 (tGFP-tagged) - Human solute carrier family 19, member 3 (SLC19A3) 10 ug
$489.00 $657.00
SC108121 SLC19A3 (untagged)-Human solute carrier family 19, member 3 (SLC19A3) 10 ug
$457.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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