PARP3 (NM_005485) Human Untagged Clone
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PARP3 |
| Synonyms | ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_005485 |
| Insert Size | 1602 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_005485.5 |
| RefSeq Size | 2416 bp |
| RefSeq ORF | 1602 bp |
| Locus ID | 10039 |
| UniProt ID | Q9Y6F1 |
| Cytogenetics | 3p21.2 |
| Domains | PARP, PARP_reg |
| Protein Families | Druggable Genome |
| Protein Pathways | Base excision repair |
| MW | 60.1 kDa |
| Summary | The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2008 Transcript Variant: This variant (2) differs in the 5' UTR and uses a downstream translational start codon, compared to variant 1. The resulting isoform (b) is shorter at the N-terminus, compared to isoform a. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_005485" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC204308 | PARP3 (Myc-DDK-tagged)-Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2 | 10 ug |
$496.00
|
|
| RC204308L1 | Lenti ORF clone of Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2, Myc-DDK-tagged | 10 ug |
$796.00
|
|
| RC204308L2 | Lenti ORF clone of Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2, mGFP tagged | 10 ug |
$796.00
|
|
| RC204308L3 | Lenti ORF clone of Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2, Myc-DDK-tagged | 10 ug |
$796.00
|
|
| RC204308L4 | Lenti ORF clone of Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2, mGFP tagged | 10 ug |
$796.00
|
|
| RG204308 | PARP3 (tGFP-tagged) - Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2 | 10 ug |
$489.00
$696.00
|
|
| SC319646 | PARP3 (untagged)-Human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2 | 10 ug |
$496.00
|
|
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