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KIRREL2 (NM_032123) Human Untagged Clone

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SKU
SC305401
KIRREL2 (untagged)-Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1
  $649.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol KIRREL2
Synonyms FILTRIN; NEPH3; NLG1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>SC305401 representing NM_032123.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGCTCAGGATGCGGGTCCCCGCCCTCCTCGTCCTCCTCTTCTGCTTCAGAGGGAGAGCAGGCCCGTCG
CCCCATTTCCTGCAACAGCCAGAGGACCTGGTGGTGCTGCTGGGGGAGGAAGCCCGGCTGCCGTGTGCT
CTGGGCGCCTACTGGGGGCTAGTTCAGTGGACTAAGAGTGGGCTGGCCCTAGGGGGCCAAAGGGACCTA
CCAGGGTGGTCCCGGTACTGGATATCAGGGAATGCAGCCAATGGCCAGCATGACCTCCACATTAGGCCC
GTGGAGCTAGAGGATGAAGCATCATATGAATGTCAGGCTACACAAGCAGGCCTCCGCTCCAGACCAGCC
CAACTGCACGTGCTGGTCCCCCCAGAAGCCCCCCAGGTGCTGGGCGGCCCCTCTGTGTCTCTGGTTGCT
GGAGTTCCTGCGAACCTGACATGTCGGAGCCGTGGGGATGCCCGCCCTACCCCTGAATTGCTGTGGTTC
CGAGATGGGGTCCTGTTGGATGGAGCCACCTTCCATCAGACCCTGCTGAAGGAAGGGACCCCTGGGTCA
GTGGAGAGCACCTTAACCCTGACCCCTTTCAGCCATGATGATGGAGCCACCTTTGTCTGCCGGGCCCGG
AGCCAGGCCCTGCCCACAGGAAGAGACACAGCTATCACACTGAGCCTGCAGTACCCCCCAGAGGTGACT
CTGTCTGCTTCGCCACACACTGTGCAGGAGGGAGAGAAGGTCATTTTCCTGTGCCAGGCCACAGCCCAG
CCTCCTGTCACAGGCTACAGGTGGGCAAAAGGGGGCTCTCCGGTGCTCGGGGCCCGCGGGCCAAGGTTA
GAGGTCGTGGCAGACGCCTCGTTCCTGACTGAGCCCGTGTCCTGCGAGGTCAGCAACGCCGTGGGTAGC
GCCAACCGCAGTACTGCGCTGGATGTGCTGTTTGGGCCGATTCTGCAGGCAAAGCCGGAGCCCGTGTCC
GTGGACGTGGGGGAAGACGCTTCCTTCAGCTGCGCCTGGCGCGGGAACCCGCTTCCACGGGTAACCTGG
ACCCGCCGCGGTGGCGCGCAGGTGCTGGGCTCTGGAGCCACACTGCGTCTTCCGTCGGTGGGGCCCGAG
GACGCAGGCGACTATGTGTGCAGAGCTGAGGCTGGGCTATCGGGCCTGCGGGGCGGCGCCGCGGAGGCT
CGGCTGACTGTGAACGCTCCCCCAGTAGTGACCGCCCTGCACTCTGCGCCTGCCTTCCTGAGGGGCCCT
GCTCGCCTCCAGTGTCTGGTTTTCGCCTCTCCCGCCCCAGATGCCGTGGTCTGGTCTTGGGATGAGGGC
TTCCTGGAGGCGGGGTCGCAGGGCCGGTTCCTGGTGGAGACATTCCCTGCCCCAGAGAGCCGCGGGGGA
CTGGGTCCGGGCCTGATCTCTGTGCTACACATTTCGGGGACCCAGGAGTCTGACTTTAGCAGGAGCTTT
AACTGCAGTGCCCGGAACCGGCTGGGCGAGGGAGGTGCCCAGGCCAGCCTGGGCCGTAGAGACTTGCTG
CCCACTGTGCGGATAGTGGCCGGAGTGGCCGCTGCCACCACAACTCTCCTTATGGTCATCACTGGGGTG
GCCCTCTGCTGCTGGCGCCACAGCAAGGCCTCAGCCTCTTTCTCCGAGCAAAAGAACCTGATGCGAATC
CCTGGCAGCAGCGACGGCTCCAGTTCACGAGGTCCTGAAGAAGAGGAGACAGGCAGCCGCGAGGACCGG
GGCCCCATTGTGCACACTGACCACAGTGATCTGGTTCTGGAGGAGGAAGGGACTCTGGAGACCAAGGAC
CCAACCAACGGTTACTACAAGGTCCGAGGAGTCAGTCCACCCGCGTCTCCAGACTCACGTGTGACATCT
TTCCAATGGAAGAGTCCTGGGATCTCCAACTTGCCATAA
ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites SgfI-MluI |
ACCN NM_032123
Insert Size 1902 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_032123.6
RefSeq Size 2582 bp
RefSeq ORF 1902 bp
Locus ID 84063
UniProt ID Q6UWL6
Cytogenetics 19q13.12
Protein Families Transmembrane
MW 67.1 kDa
Summary This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. provided by RefSeq, Jul 2016
Transcript Variant: This variant (1) differs in the 5' UTR and contains an alternate intron in the 3' coding region, which results in a frameshift compared to variant 3. The encoded isoform (a) is shorter and has a distinct C-terminus compared to isoform c.
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Documents
Resources
"NM_032123" in other vectors (6)
SKU Description Size Price
RC215296 KIRREL2 (Myc-DDK-tagged)-Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1 10 ug
$589.00
RC215296L1 Lenti ORF clone of Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1, Myc-DDK-tagged 10 ug
$889.00
RC215296L2 Lenti ORF clone of Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1, mGFP tagged 10 ug
$889.00
RC215296L3 Lenti ORF clone of Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1, Myc-DDK-tagged 10 ug
$889.00
RC215296L4 Lenti ORF clone of Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1, mGFP tagged 10 ug
$889.00
RG215296 KIRREL2 (tGFP-tagged) - Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1 10 ug
$489.00 $789.00

file-alt Citations

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