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NRDE2 (NM_017970) Human Untagged Clone

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SKU
SC304549
NRDE2 (untagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1
  $1,622.00
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Other products for "NRDE2 or NM_017970"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol NRDE2
Synonyms C14orf102
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Restriction Sites SgfI-MluI |
ACCN NM_017970
Insert Size 3495 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_017970.3
RefSeq Size 4026 bp
RefSeq ORF 3495 bp
Locus ID 55051
UniProt ID Q9H7Z3
Cytogenetics 14q32.11
MW 132.7 kDa
Summary Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation (PubMed:30842217). Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation (PubMed:30842217). Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome (PubMed:30842217). By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm (PubMed:30842217).UniProtKB/Swiss-Prot Function
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"NM_017970" in other vectors (6)
SKU Description Size Price
RC224847 NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 10 ug
$1,520.00
RC224847L1 Lenti-ORF clone of NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 10 ug
$1,820.00
RC224847L2 Lenti-ORF clone of NRDE2 (mGFP-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 10 ug
$1,820.00
RC224847L3 Lenti-ORF clone of NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 10 ug
$1,820.00
RC224847L4 Lenti-ORF clone of NRDE2 (mGFP-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 10 ug
$1,820.00
RG224847 NRDE2 (tGFP-tagged) - Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 10 ug
$1,720.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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