NAV3 (NM_014903) Human Tagged ORF Clone
$2,888.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | NAV3 |
| Synonyms | POMFIL1; STEERIN3; unc53H3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_014903 |
| ORF Size | 6999 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq Size | 9644 bp |
| RefSeq ORF | 7092 bp |
| Locus ID | 89795 |
| UniProt ID | Q8IVL0 |
| Cytogenetics | 12q21.2 |
| Domains | AAA, CH |
| MW | 249.86 kDa |
| Summary | This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_014903" in other vectors (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC222713L1 | Lenti ORF clone of Human neuron navigator 3 (NAV3), Myc-DDK-tagged | 10 ug |
$3,188.00
|
|
| RG222713 | NAV3 (tGFP-tagged) - Human neuron navigator 3 (NAV3) | 10 ug |
$3,088.00
|
|
| SC308910 | NAV3 (untagged)-Human neuron navigator 3 (NAV3) | 10 ug |
$2,926.00
|
|
Citations
Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression
Cohen-Dvashi, Ben-Chetrit, Russell et al
EMBO Mol Med (2015)
Cohen-Dvashi, Ben-Chetrit, Russell et al
EMBO Mol Med (2015)
Cited by 47
AI Summary: OriGene contributed to this study by providing the human NAV3 cDNA, which was used to investigate the role of NAV3 in cell migration and breast cancer progression.
Snippet: Materials and Methods Reagents and antibodies Chemotaxis and cell tracking slides were from Ibidi (Munich, Germany), and glass‐bottom dishes were from MaTek (Ashland, MA). A murine monoclonal antibody to NAV3 was generated in our laboratory. …The cDNA of human NAV3 was purchased from OriGene (Rockville, MD)
Showing 1-1 of 1 papers.
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in shipping.
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