BAX (NM_138763) Human Tagged ORF Clone
$150.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | BAX |
| Synonyms | BCL2L4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_138763 |
| ORF Size | 429 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_138763.4 |
| RefSeq Size | 741 bp |
| RefSeq ORF | 432 bp |
| Locus ID | 581 |
| UniProt ID | Q07812 |
| Cytogenetics | 19q13.33 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, Neurotrophin signaling pathway, p53 signaling pathway, Pathways in cancer, Prion diseases |
| MW | 15.6 kDa |
| Summary | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. provided by RefSeq, Dec 2019 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_138763" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC222409L1 | Lenti ORF clone of Human BCL2-associated X protein (BAX), transcript variant delta, Myc-DDK-tagged | 10 ug |
$450.00
|
|
| RC222409L2 | Lenti ORF clone of Human BCL2-associated X protein (BAX), transcript variant delta, mGFP tagged | 10 ug |
$450.00
|
|
| RC222409L3 | Lenti ORF clone of Human BCL2-associated X protein (BAX), transcript variant delta, Myc-DDK-tagged | 10 ug |
$450.00
|
|
| RC222409L4 | Lenti ORF clone of Human BCL2-associated X protein (BAX), transcript variant delta, mGFP tagged | 10 ug |
$450.00
|
|
| RG222409 | BAX (tGFP-tagged) - Human BCL2-associated X protein (BAX), transcript variant delta | 10 ug |
$489.00
|
|
| SC306076 | BAX (untagged)-Human BCL2-associated X protein (BAX), transcript variant delta | 10 ug |
$150.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
