PTPH1 (PTPN3) (NM_002829) Human Tagged ORF Clone
SKU
RC215851
PTPN3 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1
$836.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | PTPH1 |
| Synonyms | PTP-H1; PTPH1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_002829 |
| ORF Size | 2739 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_002829.4 |
| RefSeq Size | 4104 bp |
| RefSeq ORF | 2742 bp |
| Locus ID | 5774 |
| UniProt ID | P26045, B7Z9V1, Q8N4S3, E9PGU7 |
| Cytogenetics | 9q31.3 |
| Domains | B41, PDZ, PTPc_motif, Y_phosphatase |
| Protein Families | Druggable Genome, Phosphatase |
| MW | 103.8 kDa |
| Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2009 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_002829" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC215851L1 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1, Myc-DDK-tagged | 10 ug |
$1,136.00
|
|
| RC215851L2 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1, mGFP tagged | 10 ug |
$1,136.00
|
|
| RC215851L3 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1, Myc-DDK-tagged | 10 ug |
$1,136.00
|
|
| RC215851L4 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1, mGFP tagged | 10 ug |
$1,136.00
|
|
| RG215851 | PTPN3 (tGFP-tagged) - Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1 | 10 ug |
$789.00
$1,036.00
|
|
| SC107908 | PTPN3 (untagged)-Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1 | 10 ug |
$837.00
|
|
Citations
Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein
Genera, Quioc-Salomon, Nourisson et al
Sci Rep (2021) 11 (1), 944 DOI: 10.1038/s41598-020-79580-9
Genera, Quioc-Salomon, Nourisson et al
Sci Rep (2021) 11 (1), 944 DOI: 10.1038/s41598-020-79580-9
Cited by 14
AI Summary: OriGene’s pCMV6-PTPN3 plasmid (RC15851) was used to generate HepG2-NTCP-PTPN3 cells stably expressing PTPN3, enabling the authors to investigate the molecular interaction between PTPN3 and the hepatitis B virus core protein in this study.
Snippet: … HepG2-NTCP-PTPN3 cells are derived from HepG2-NTCP cells, and stably express PTPN3. pCMV6-PTPN3 plasmid was from ORIGENE (reference RC15851). …pCMV6-PTPN3 plasmid was from ORIGENE (reference RC15851). …
Showing 1-1 of 1 papers.
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