eIF4GII (EIF4G3) (NM_003760) Human Tagged ORF Clone
- TrueORF®
SKU
RC212591
EIF4G3 (Myc-DDK-tagged)-Human eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), transcript variant 3
$589.00
$1,356.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | eIF4GII |
| Synonyms | eIF-4G 3; eIF4G 3; eIF4GII |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_003760 |
| ORF Size | 4755 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_003760.2, NP_003751.2 |
| RefSeq Size | 5880 bp |
| RefSeq ORF | 4758 bp |
| Locus ID | 8672 |
| UniProt ID | O43432, Q59GJ0 |
| Cytogenetics | 1p36.12 |
| Domains | eIF5C, MA3, MIF4G |
| Protein Families | Transcription Factors |
| Protein Pathways | Viral myocarditis |
| MW | 176.5 kDa |
| Summary | The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. provided by RefSeq, May 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_003760" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC212591L3 | Lenti-ORF clone of EIF4G3 (Myc-DDK-tagged)-Human eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), transcript variant 3 | 10 ug |
$1,656.00
|
|
| RC212591L4 | Lenti-ORF clone of EIF4G3 (mGFP-tagged)-Human eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), transcript variant 3 | 10 ug |
$1,656.00
|
|
| RG212591 | EIF4G3 (tGFP-tagged) - Human eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), transcript variant 3 | 10 ug |
$789.00
$1,556.00
|
|
| SC117780 | EIF4G3 (untagged)-Human eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), transcript variant 3 | 10 ug |
$1,357.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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