NBPF15 (NM_173638) Human Tagged ORF Clone
SKU
RC212377
NBPF15 (Myc-DDK-tagged)-Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2
$920.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | NBPF15 |
| Synonyms | AB14; AG3; NBPF16 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_173638 |
| ORF Size | 2010 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_173638.2, NP_775909.1 |
| RefSeq Size | 4272 bp |
| RefSeq ORF | 2013 bp |
| Locus ID | 284565 |
| UniProt ID | Q8N660, B4DRP3 |
| Cytogenetics | 1q21.1 |
| MW | 77.5 kDa |
| Summary | This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. provided by RefSeq, May 2013 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_173638" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC212377L1 | Lenti ORF clone of Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2, Myc-DDK-tagged | 10 ug |
$1,220.00
|
|
| RC212377L2 | Lenti ORF clone of Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2, mGFP tagged | 10 ug |
$1,220.00
|
|
| RC212377L3 | Lenti ORF clone of Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2, Myc-DDK-tagged | 10 ug |
$1,220.00
|
|
| RC212377L4 | Lenti ORF clone of Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2, mGFP tagged | 10 ug |
$1,220.00
|
|
| RG212377 | NBPF15 (tGFP-tagged) - Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2 | 10 ug |
$1,120.00
|
|
| SC107071 | NBPF15 (untagged)-Human neuroblastoma breakpoint family, member 15 (NBPF15), transcript variant 2 | 10 ug |
$921.00
|
|
Citations
DUF1220 protein domains drive proliferation in human neural stem cells and are associated with increased cortical volume in anthropoid primates
Keeney, Davis, Siegenthaler et al
Brain Struct Funct (2014)
Keeney, Davis, Siegenthaler et al
Brain Struct Funct (2014)
Cited by 66
Showing 1-1 of 1 papers.
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in shipping.
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