VCP (NM_007126) Human Tagged ORF Clone
$738.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | VCP |
| Synonyms | CDC48; FTDALS6; p97; TERA |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_007126 |
| ORF Size | 2418 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_007126.5 |
| RefSeq Size | 3859 bp |
| RefSeq ORF | 2421 bp |
| Locus ID | 7415 |
| UniProt ID | P55072, V9HW80 |
| Cytogenetics | 9p13.3 |
| Domains | AAA, cdc48_N |
| MW | 89.3 kDa |
| Summary | This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. provided by RefSeq, Aug 2017 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_007126" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC211130L1 | Lenti ORF clone of Human valosin containing protein (VCP), Myc-DDK-tagged | 10 ug |
$1,038.00
|
|
| RC211130L2 | Lenti ORF clone of Human valosin containing protein (VCP), mGFP tagged | 10 ug |
$1,038.00
|
|
| RC211130L3 | Lenti ORF clone of Human valosin containing protein (VCP), Myc-DDK-tagged | 10 ug |
$1,038.00
|
|
| RC211130L4 | Lenti ORF clone of Human valosin containing protein (VCP), mGFP tagged | 10 ug |
$1,038.00
|
|
| RG211130 | VCP (tGFP-tagged) - Human valosin containing protein (VCP) | 10 ug |
$789.00
$938.00
|
|
| SC125280 | VCP (untagged)-Human valosin containing protein (VCP) | 10 ug |
$739.00
|
|
Citations
Membralin Assembles a MAN1B1-VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation
Zhang, Lu, Li et al
Adv Sci (Weinh) (2025)
Zhang, Lu, Li et al
Adv Sci (Weinh) (2025)
Cited by 7
AI Summary: OriGene products, specifically the pCMV6-CD3D-Myc-FLAG, pCMV6-NCSTN-Myc-FLAG, and pCMV6-VCP-Myc-FLAG plasmids (Cat# RC202082, RC218041, RC219485, RC210010, RC212646, RC211130), were used in this study to express and analyze key proteins involved in the Membralin-MAN1B1-VCP complex that mediates selective degradation of foreign glycoproteins in the endoplasmic reticulum.
Membralin Selects Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation
Zheng, Zhang, Lu et al
Research Square (2025)
Zheng, Zhang, Lu et al
Research Square (2025)
Cited by 1
AI Summary: OriGene products, including pCMV6-SERPINA1-Myc-Flag, pCMV6-COL2A1-Myc-Flag, pCMV6-DYSF-Myc-Flag, pCMV6-CD3D-Myc-Flag, pCMV6-NCSTN-Myc-Flag, and pCMV6-VCP-Myc-FLAG, were used as expression plasmids to study the roles of various proteins in Membralin-mediated degradation of foreign glycoproteins in the endoplasmic reticulum.
Snippet: pCDNA3.1-NHK was provided by Richard Sifers. pCMV6-SERPINA1-Myc-Flag, pCMV6-COL2A1-Myc-Flag, pCMV6-DYSF-Myc-Flag, pCMV6-CD3D-Myc-Flag, pCMV6-NCSTN-Myc-Flag, and pCMV6-VCP-Myc-FLAG were ordered from Origene (Cat# RC202082, RC218041, RC219485, RC210010, RC212646, RC211130). SERPINA1/AAT, NPC1, COL2A1, and DYSF mutants and pCMV6-VCP-His were created by PCR and ASiSI/MluI digestion followed by homol
Showing 1-2 of 2 papers.
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