ILRUN (NM_024294) Human Tagged ORF Clone
SKU
RC209929
C6orf106 (Myc-DDK-tagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | ILRUN |
| Synonyms | C6orf106; dJ391O22.4; FP852 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_024294 |
| ORF Size | 894 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_024294.4 |
| RefSeq Size | 4433 bp |
| RefSeq ORF | 897 bp |
| Locus ID | 64771 |
| UniProt ID | Q9H6K1, A0A024RCW2 |
| Cytogenetics | 6p21.31 |
| MW | 32.9 kDa |
| Summary | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_024294" in other vectors (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC209929L3 | Lenti ORF clone of Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1, Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC209929L4 | Lenti ORF clone of Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1, mGFP tagged | 10 ug |
$600.00
|
|
| RG209929 | C6orf106 (tGFP-tagged) - Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1 | 10 ug |
$489.00
$500.00
|
|
| SC112260 | C6orf106 (untagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1 | 10 ug |
$300.00
|
|
| SC322752 | C6orf106 (untagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1 | 10 ug |
$300.00
|
|
Citations
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway
Li, Dong, Zhou et al
Mol. Cell. Biochem. (2018)
Li, Dong, Zhou et al
Mol. Cell. Biochem. (2018)
AI Summary: OriGene products pCMV6-ddk-myc and pCMV6-ddk-myc-C6orf106 (RC209929) were used in this study to manipulate C6orf106 expression in pancreatic cancer cells, enabling the investigation of its role in cancer cell invasion and proliferation.
Snippet: trypsin (Invitrogen). Plasmid transfection and small interfering RNA treatment Plasmids pCMV6-ddk-myc and pCMV6-ddk-myc- C6orf106 (RC209929) were purchased from Origene (Rockville, MD, USA). C6orf106-siRNA (sc
A novel biomarker C6orf106 promotes the malignant progression of breast cancer
Jiang, Zhang, Zhang et al
Tumour Biol. (2015)
Jiang, Zhang, Zhang et al
Tumour Biol. (2015)
Cited by 14
AI Summary: OriGene contributed to this study by providing the pCMV6-ddk-myc empty vector and pCMV6-ddk-myc-C6orf106 plasmids, which were used to investigate the role of C6orf106 in breast cancer cell proliferation and invasion.
Snippet: (CA, USA). The pCMV6-ddk-myc empty vector and pCMV6-ddk-myc- C6orf106 were purchased from Origene (Rockville, MD, USA). MDA-MB-231, BT-549, and MCF-10A cells were Tumor Biol. Page 3. seeded at 1×105 cells per 35-mm well. ... Cite SaveSaving
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn
Zhang, Miao, Yu et al
Tumour Biol. (2015)
Zhang, Miao, Yu et al
Tumour Biol. (2015)
Cited by 10
Snippet: Plasmid transfection and small interfering RNA treatment The pCMV6-ddk-myc empty vector and pCMV6-ddk-myc- C6orf106 were purchased from Origene (Rockville, MD, USA). C6orf106-siRNA (sc-95499) and NC-siRNA (sc- 37007) were purchased from Santa Cruz ... Cite SaveSaving
Showing 1-3 of 3 papers.
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