STAT2 (NM_005419) Human Tagged ORF Clone
- TrueORF®
SKU
RC208592
STAT2 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1
$779.00
5 Days*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | STAT2 |
| Synonyms | IMD44; ISGF-3; P113; PTORCH3; STAT113 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_005419 |
| ORF Size | 2553 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_005419.4 |
| RefSeq Size | 4576 bp |
| RefSeq ORF | 2556 bp |
| Locus ID | 6773 |
| UniProt ID | P52630, R9QE65 |
| Cytogenetics | 12q13.3 |
| Domains | SH2, STAT |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Chemokine signaling pathway, Jak-STAT signaling pathway |
| MW | 97.9 kDa |
| Summary | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. provided by RefSeq, Aug 2020 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_005419" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC208592L1 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, Myc-DDK-tagged | 10 ug |
$1,079.00
|
|
| RC208592L2 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mGFP tagged | 10 ug |
$1,079.00
|
|
| RC208592L3 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, Myc-DDK-tagged | 10 ug |
$1,079.00
|
|
| RC208592L4 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mGFP tagged | 10 ug |
$1,079.00
|
|
| RG208592 | STAT2 (tGFP-tagged) - Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 | 10 ug |
$789.00
$979.00
|
|
| SC108848 | STAT2 (untagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 | 10 ug |
$780.00
|
|
Citations
Alterations of brain quantitative proteomics profiling revealed the molecular mechanisms of diosgenin against cerebral ischemia reperfusion effects
Zhang, Wang, Khurm et al
J. Proteome Res. (2020)
Zhang, Wang, Khurm et al
J. Proteome Res. (2020)
Cited by 29
AI Summary: OriGene contributed STAT2 and HIKESHI cloning plasmids, which were used to generate overexpression constructs for validating the molecular mechanisms of diosgenin against cerebral ischemia reperfusion in this study.
Snippet: Page 1. 1 Alterations of brain quantitative proteomics profiling revealed the molecular mechanisms of diosgenin against cerebral ischemia reperfusion effects Xinxin Zhang 1, 2, Xingbin Wang 1, Muhammad Khurm 1, Guanqun Zhan 1, Hui Zhang 1;The cloning plasmids inserting the open reading frame (ORF) fragment of the target genes containing STAT2 and HIKESHI were purchased from OriGene Technologies, Inc. …
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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