UNC45A (NM_001039675) Human Tagged ORF Clone
SKU
RC206953
UNC45A (Myc-DDK-tagged)-Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3
$851.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | UNC45A |
| Synonyms | GC-UNC45; GCUNC-45; GCUNC45; IRO039700; OOHE; SMAP-1; SMAP1; UNC-45A |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001039675 |
| ORF Size | 2787 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001039675.1, NP_001034764.1 |
| RefSeq Size | 4035 bp |
| RefSeq ORF | 2790 bp |
| Locus ID | 55898 |
| UniProt ID | Q9H3U1 |
| Cytogenetics | 15q26.1 |
| MW | 101.7 kDa |
| Summary | This gene encodes a regulatory component of the progesterone receptor/heat shock protein 90 chaperoning complex, which functions in the assembly and folding of the progesterone receptor. The encoded protein is thought to be essential for normal cell proliferation, and for the accumulation of myosin during development of muscle cells. provided by RefSeq, Sep 2018 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001039675" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC206953L1 | Lenti ORF clone of Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3, Myc-DDK-tagged | 10 ug |
$1,151.00
|
|
| RC206953L2 | Lenti ORF clone of Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3, mGFP tagged | 10 ug |
$1,151.00
|
|
| RC206953L3 | Lenti ORF clone of Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3, Myc-DDK-tagged | 10 ug |
$1,151.00
|
|
| RC206953L4 | Lenti ORF clone of Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3, mGFP tagged | 10 ug |
$1,151.00
|
|
| RG206953 | UNC45A (tGFP-tagged) - Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3 | 10 ug |
$789.00
$1,051.00
|
|
| SC310777 | UNC45A (untagged)-Human unc-45 homolog A (C. elegans) (UNC45A), transcript variant 3 | 10 ug |
$937.00
|
|
Citations
The UNC45A–MYO5B Axis in Enterohepatic Disorders
Zhou
University of Groningen (2026)
Zhou
University of Groningen (2026)
AI Summary: OriGene’s pCMV6-Entry-UNC45A plasmid (RC206953) provided the full-length human UNC45A sequence used for generating expression constructs and introducing patient-derived mutations, enabling mechanistic studies of UNC45A’s role in epithelial polarity and trafficking in this paper.
Snippet: ll-length tagged human UNC45A sequence was amplified from plasmid pCMV6- Entry-UNC45A (Origene RC206953) through polymerase chain reaction. Amplified UNC45A-myc-FLAG was inserted into pENTR1a vectors, and then the myc tag was deleted. Patient-derived point mutations were produced on the myc tag deleted pE NTR1a plasmid. The Q5 Site
A molecular mechanism of intrahepatic cholestasis in osteo-oto-hepato-enteric syndrome
Zhou, Lin, Imhann et al
Cell Mol Gastroenterol Hepatol (2026)
Zhou, Lin, Imhann et al
Cell Mol Gastroenterol Hepatol (2026)
Cited by 1
A Functional Relationship Between UNC45A and MYO5B Connects Two Rare Diseases With Shared Enteropathy
Li, Zhou, Sun et al
Cell Mol Gastroenterol Hepatol (2022) 14 (2), 295-310 DOI: 10.1016/j.jcmgh.2022.04.006
Li, Zhou, Sun et al
Cell Mol Gastroenterol Hepatol (2022) 14 (2), 295-310 DOI: 10.1016/j.jcmgh.2022.04.006
Cited by 21
AI Summary: OriGene’s pCMV6-Entry-UNC45A plasmid (RC206953) was used to amplify full-length human UNC45A for expression and mutagenesis studies, enabling the investigation of UNC45A’s functional relationship with MYO5B in this research.
Snippet: HepG2 UNC45A KO2 were both generated with oligos UNC45A CRISPR 2 forward and UNC45A CRISPR 2 reverse. Plasmids Full-length tagged human UNC45A sequence was amplified from plasmid pCMV6-Entry-UNC45A (Origene RC206953) through polymerase chain reaction. Amplified UNC45A-myc-FLAG was inserted into pENTR1a vectors, and then the myc tag was deleted. Patient-derived point mutations were produced on the;Full-length tagged human UNC45A sequence was amplified from plasmid pCMV6-Entry-UNC45A (Origene RC206953) through polymerase chain reaction. Amplified UNC45A-myc-FLAG was inserted into pENTR1a vectors, and then the myc tag was deleted
Showing 1-3 of 3 papers.
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