BIGM103 (SLC39A8) (NM_022154) Human Tagged ORF Clone
SKU
RC204200
SLC39A8 (Myc-DDK-tagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | BIGM103 |
| Synonyms | BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_022154 |
| ORF Size | 1380 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_022154.5, NP_071437.3 |
| RefSeq Size | 3309 bp |
| RefSeq ORF | 1383 bp |
| Locus ID | 64116 |
| UniProt ID | Q9C0K1, A0A024RDG0 |
| Cytogenetics | 4q24 |
| Domains | Zip |
| Protein Families | Transmembrane |
| MW | 49.5 kDa |
| Summary | This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. provided by RefSeq, Oct 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_022154" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC204200L1 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC204200L2 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, mGFP tagged | 10 ug |
$757.00
|
|
| RC204200L3 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC204200L4 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, mGFP tagged | 10 ug |
$757.00
|
|
| RG204200 | SLC39A8 (tGFP-tagged) - Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 | 10 ug |
$489.00
$657.00
|
|
| SC112817 | SLC39A8 (untagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 | 10 ug |
$457.00
|
|
| SC320928 | SLC39A8 (untagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 | 10 ug |
$457.00
|
|
Citations
Forced Overexpression and Knockout Analysis of SLC30A and SLC39A Family Genes Suggests Their Involvement in Establishing Resistance to Cisplatin in Human Cancer Cells
Kamynina, Rozenberg, Kushchenko et al
Int J Mol Sci (2024) 25 (22) DOI: 10.3390/ijms252212049
Kamynina, Rozenberg, Kushchenko et al
Int J Mol Sci (2024) 25 (22) DOI: 10.3390/ijms252212049
Cited by 7
AI Summary: OriGene’s SLC39A14, SLC39A8, SLC30A3, and SLC30A10 ORF clones were used to construct lentiviral vectors for gene overexpression studies, enabling the investigation of these genes’ roles in cisplatin resistance in human cancer cells.
Snippet: I, USA) in which the GFP was replaced by the puromycin resistance selection marker and the SLC39A8 (NM_022154.5), SLC30A3 (NM_003459.5), SLC30A10 (NM_018713.3), and SLC39A14 (NM_015359.6) ORF clones (Origene) were utilized for lentiviral vector construction. The genes SLC39A14, SLC39A8, SLC30A3, and SLC30A10 were amplified using high-fidelity DNA polymerase with primers designed to include EcoRI a
Showing 1-1 of 1 papers.
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