MAX (NM_145114) Human Tagged ORF Clone
$150.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | MAX |
| Synonyms | bHLHd4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_145114 |
| ORF Size | 288 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_145114.2 |
| RefSeq Size | 937 bp |
| RefSeq ORF | 291 bp |
| Locus ID | 4149 |
| UniProt ID | P61244 |
| Cytogenetics | 14q23.3 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | MAPK signaling pathway, Pathways in cancer, Small cell lung cancer |
| MW | 11.5 kDa |
| Summary | The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2012 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_145114" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC203944L3 | Lenti ORF clone of Human MYC associated factor X (MAX), transcript variant 4, Myc-DDK-tagged | 10 ug |
$450.00
|
|
| RC203944L4 | Lenti ORF clone of Human MYC associated factor X (MAX), transcript variant 4, mGFP tagged | 10 ug |
$450.00
|
|
| RG203944 | MAX (tGFP-tagged) - Human MYC associated factor X (MAX), transcript variant 4 | 10 ug |
$489.00
|
|
| SC324151 | MAX (untagged)-Human MYC associated factor X (MAX), transcript variant 4 | 10 ug |
$150.00
|
|
Citations
MYC-associated protein X binding with the variant rs72780850 in RNA helicase DEAD box 1 for susceptibility to neuroblastoma
Jin, Shi, Wang et al
Sci China Life Sci (2021) 64 (6), 991-999 DOI: 10.1007/s11427-020-1784-7
Jin, Shi, Wang et al
Sci China Life Sci (2021) 64 (6), 991-999 DOI: 10.1007/s11427-020-1784-7
Cited by 11
AI Summary: OriGene products contributed to this study by providing the pCMV6-DDX1 expression plasmid, which was used to investigate the functional effects of DDX1 on neuroblastoma susceptibility.
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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