CCDC22 (NM_014008) Human Tagged ORF Clone
$584.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | CCDC22 |
| Synonyms | CXorf37; JM1; RTSC2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_014008 |
| ORF Size | 1881 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_014008.3 |
| RefSeq Size | 2333 bp |
| RefSeq ORF | 1884 bp |
| Locus ID | 28952 |
| UniProt ID | O60826, A0A024QZ03 |
| Cytogenetics | Xp11.23 |
| MW | 70.8 kDa |
| Summary | This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. provided by RefSeq, Aug 2013 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_014008" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC201585L1 | Lenti ORF clone of Human coiled-coil domain containing 22 (CCDC22), Myc-DDK-tagged | 10 ug |
$884.00
|
|
| RC201585L2 | Lenti ORF clone of Human coiled-coil domain containing 22 (CCDC22), mGFP tagged | 10 ug |
$884.00
|
|
| RC201585L3 | Lenti ORF clone of Human coiled-coil domain containing 22 (CCDC22), Myc-DDK-tagged | 10 ug |
$884.00
|
|
| RC201585L4 | Lenti ORF clone of Human coiled-coil domain containing 22 (CCDC22), mGFP tagged | 10 ug |
$884.00
|
|
| RG201585 | CCDC22 (tGFP-tagged) - Human coiled-coil domain containing 22 (CCDC22) | 10 ug |
$489.00
$784.00
|
|
| SC115211 | CCDC22 (untagged)-Human coiled-coil domain containing 22 (CCDC22) | 10 ug |
$585.00
|
|
| SC323782 | CCDC22 (untagged)-Human coiled-coil domain containing 22 (CCDC22) | 10 ug |
$585.00
|
|
Citations
Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome
Kolanczyk, Krawitz, Hecht et al
Eur. J. Hum. Genet. (2014)
Kolanczyk, Krawitz, Hecht et al
Eur. J. Hum. Genet. (2014)
Cited by 74
AI Summary: OriGene’s pCMV6-Flag-CCDC22 vectors were used for transient transfection experiments to study the functional effects of the CCDC22 variant identified in the patients.
Snippet: essential medium (MEM) with 10% fetal bovine serum, 100 U/ml penicillin, 100 g/ml streptomycin, and 2 mM glutamine (all reagents from Sigma-Aldrich GmbH) at 37 °C with 5% CO 2 . Cells were transiently transfected with pCMV6-Flag-CCDC22 vectors (OriGene, ... Cite SaveSaving
RME-8 coordinates the WASH complex with the retromer SNX-BAR dimer to control endosomal tubulation
Freeman, Hesketh, Seaman
J. Cell. Sci. (2014)
Freeman, Hesketh, Seaman
J. Cell. Sci. (2014)
Cited by 113
AI Summary: OriGene products CCDC93-GFP and CCDC22-myc were used in this study to investigate the molecular interactions involved in endosomal tubulation and protein sorting.
Snippet: GFP-VPS35 is described in Gokool et al. (2007a). CCDC93-GFP and CCDC22-myc 551 were from Origene
Showing 1-2 of 2 papers.
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